The BJO editorial, titled “The Many Enigmas of Intermittent Exotropia,”2 recounts a meeting of the Squint Club (an annual gathering of strabismus experts) several years earlier, at which Arthur Rosenbaum (now deceased) presented a paper contending that intermittent exotropia was the most perplexing and difficult form of strabismus. A Randomized Trial Evaluating Short-term Effectiveness of Overminus Lenses in Children 3 to 6 Years of Age with Intermittent Exotropia. Affiliations. 2019 Sep;126(9):1249-1260. doi: 10.1016/j.ophtha.2019.01.015. This site needs JavaScript to work properly. Two hundred one children 12 to 35 months of age with untreated IXT meeting the following criteria: (1) IXT at distance OR constant exotropia at distance and either IXT or exophoria at near, and (2) 15-prism diopter (Δ) or more exodeviation at distance or near by prism and alternate cover test (PACT) but at least 10 Δ exodeviation at distance by PACT. For the observation and patching groups, respectively, 6-month mean PACT measurements were 27.9 Δ versus 24.9 Δ at distance (P = 0.02) and 19.3 Δ versus 17.0 Δ at near (P = 0.10); 6-month mean exotropia control scores were 2.8 versus 2.3 points at distance (P = 0.02) and 1.4 versus 1.1 points at near (P = 0.26). x���ms�8����*��� Development of a core outcome set for amblyopia, strabismus and ocular motility disorders: a review to identify outcome measures. 2 0 obj '�2�zĭkó��  |  Three-Year Observation of Children 3 to 10 Years of Age with Untreated Intermittent Exotropia. (Ophthalmology 2015;122:1543-6). doi: 10.1016/j.ophtha.2015.08.047. 2020 Jul 4;32(3):217-225. doi: 10.4103/JOCO.JOCO_81_20. Re: Brodsky et al. 10 0 obj <> <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 10 0 R/Group<>/Tabs/S/StructParents 2>> Relationship among clinical factors in childhood intermittent exotropia.  |  2019 Nov;42(9):1007-1019. doi: 10.1016/j.jfo.2018.12.031. A randomized trial comparing part-time patching with observation for children 3 to 10 years of age with intermittent exotropia. <> Sometimes the exotropia is noticed more when the patient is looking in the distance. D��E�g��X=­^�ˋ�U�/_�h�v�_�7@����������;�Tw��#�Z�ѯ�����C�����3M�J��}[~�{߽^ �Ŝ��������*!��n;�*�m�Tඊz�� bD�6�� � Epub 2017 Jun 28. ����}�3q�� sa��`��<3�gʭ�?�v��� ZUmg`�U����mS��-��yֽ����0��EI���`�f����gRpv����ړ��r0�KR��'֞�F'a�[(�F��)��`b�Iht"��bY�X����ړ��dr��8�Lb=�VkB!f�R��eO}��Ԟ�F@�Y�ԏ�T��JLl�3�q&~`n.��z.g��_PY���9��q3�K�B� O��#�*T�dX�����B-t� N�L? stream Pediatric Eye Disease Investigator Group. 9 0 obj COVID-19 is an emerging, rapidly evolving situation. Please select one of the following choices: PEDIG Public Website ��m°s��J����;�p�"�_%/� ��R�a��I9[�N���z�� �w��~��ZR�Fe(� [5yy�qQ�~����U2m�+[ �c���0�3����~�ќ�����M3�E�Ҍ+�R6͔mC4gL��X��=���Q�q,��7߀��$oI^��|\V 1. Ophthalmology. 5 0 obj 11 0 obj endobj ���� ��ı� ��`3| � Methods: Flow of Participants through Study, NLM 160 161 1.1 Intermittent Exotropia 3 0 obj <>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> 7 0 obj Click here if you are at a PEDIG site, PEDIG Training Website Participants: 2019 Sep;126(9):1249-1260. doi: 10.1016/j.ophtha.2019.01.015. <>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/Annots[ 17 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 28 0 R 29 0 R 32 0 R 34 0 R 35 0 R 36 0 R 38 0 R 40 0 R 41 0 R 43 0 R 44 0 R 45 0 R 48 0 R 52 0 R 53 0 R 54 0 R 56 0 R 57 0 R 61 0 R 63 0 R 64 0 R 66 0 R 69 0 R 70 0 R 71 0 R 72 0 R 74 0 R 75 0 R 79 0 R 80 0 R 81 0 R 83 0 R 84 0 R 85 0 R 87 0 R 88 0 R 89 0 R 90 0 R 91 0 R 92 0 R 93 0 R 94 0 R 96 0 R 97 0 R 98 0 R 99 0 R] /MediaBox[ 0 0 612 792] /Contents 14 0 R/Group<>/Tabs/S/StructParents 3>> Please enable it to take advantage of the complete set of features! U10 EY011751/EY/NEI NIH HHS/United States, U10 EY018810/EY/NEI NIH HHS/United States. endobj Purpose: * 2�T�����l�dFNϏG2��:��yzqN�E�Q�|�o�&¾��3��&�U@�] ��,�[�҃gj�(Q��(�fQjM��t��8J̫ J�Y��S��(]x�o%�U��,JQP��(]xVl%�U��F�i���,�)'�s��u��jz:���xvz��lwvk������ 2020 Aug 13;15(8):e0237346. Get the latest public health information from CDC: https://www.coronavirus.gov. endobj ��0����[C����^�6c7�/� ,�c��XVfX��(]�]����g��#nUv��� 6z��b,��˦V��q7�>{W��szH�Sb�q�T��t��r�F�Q(%?��T�^)��с�ѻU��a�V������|� �Ҭ���� ������,uʞU �ƅrP6{�eCց�!kE9f���;�e��| �meҶA��!�����o�PQaX\vʨ��j�i! <> endobj J AAPOS. x��Z]o�}���G�H��RQu�d�v�Ѭ��b���$Fk�"�鯿Cn��"G���X �:䙙3�p�q�.n�yK~��`ܶ����!f��?fϟ����n�,�E�N'�p��sp��,�)#��ݝ���/#�-����ݝ�ܙ�vw>&d�'����ss������9:��ęúm�Gܟ�n��/�e�����Y��S9.�5P&9���GG����2�n��Dgd�:��;��\��&�S�v3꧓��dX3N����H�$��Ti*�2FSItaM����wd�;*:�L8���c����d^��P� Q���?�\u��� �嚚���[��@�� q�X�y�m��9�Q�q�U0͓.��/��zc� D�8�4��"m�4Z$D*��O��#�џ]�]l������D��mY���-ʛ�\��! x��X]o�6}7���G{X(~S���n.��IԵE��QZ��J��׏R��H0 ���9�����-o��={���v���FWI^�?$��}�l���jۖu�\�l�[��y���.�I>�$/(����"b~i��P85w��>u�?����@���di�~�NΧ� sR�m}�yQ�m�'��Ӟ��l�6�h~�g��n�]}���Ռ����_�E��|��c�l�#�Ry�)T�(&q�Jx�$��]X��Mg��bu��� CL8r��֔a�F5[�h��̿"DfHu���k����o�z �owLjԅ��98J d�����Ӫ��4]{ ��h��ݡs]A��3⎡�@�\��û������ endobj doi: 10.1016/j.ophtha.2015.09.049. 4 0 obj Pediatric Eye Disease Investigator Group; Writing Committee, Mohney BG, Cotter SA, Chandler DL, Holmes JM, Wallace DK, Yamada T, Petersen DB, Kraker RT, Morse CL, Melia BM, Wu R. Ophthalmology. doi: 10.1371/journal.pone.0237346. stream <> Epub 2015 Jun 11. HHS Of the 177 participants (88%) completing the 6-month primary outcome examination, deterioration occurred in 4.6% (4 of 87) of the participants in the observation group and in 2.2% (2 of 90) of the participants in the patching group (difference, 2.4%; P = 0.27; 95% confidence interval, -3.8% to +9.4%). Epub 2019 Jul 10. endobj Intermittent exotropia is a condition in which there are times when one eye has drifted outwards, and other times when the eyes are straight. PEDIG Training Website Click here to be directed to the PEDIG training website : Intermittent exotropia and accommodative esotropia: distinct disorders or two ends of a spectrum? It affects twice as many females as males. �;������+�9���8g�,�8g�/�?&� Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Motor deterioration occurred in 2.3% (2 of 87) of the observation group and in 2.2% (2 of 90) of the patching group (difference, 0.08%; P = 0.55; 95% confidence interval, -5.8% to +6.1%). Pediatric Eye Disease Investigator Group, Chen AM, Holmes JM, Chandler DL, Patel RA, Gray ME, Erzurum SA, Wallace DK, Kraker RT, Jensen AA. C�����Vy'�]�����ݩ���t�;�����~��AJlPl�Ic�Ʊ�F� �i ���t�[=.�w�_���t�[�����/���_|���.����ݪ^���|��W?Vˇj�׿?|8~X�}���DFq�x|�F����8�e��ߕ̧�H�/۷o��K�1k?~z��Yp��`�oΕ���}���7���Y�0��z���m�X׻#˾}I 12 0 obj Ophthalmology. 8 0 obj Among children 12 to 35 months of age with previously untreated IXT, deterioration over 6 months was uncommon, with or without patching treatment. Copyright © 2015 American Academy of Ophthalmology. endobj D�8�f��#���y�H�T �ljdfj � Three-Year Observation of Children 3 to 10 Years of Age with Untreated Intermittent Exotropia. %���� 't�=IH G��$�v��Pyǂ~��m.��x.����3����{{��r�b�~���sU)L������x�����]���������5���,��c���ѾL�f#ׁ��2�b�~Ɂڷ����'�YV�oF�������^9 156 This study is being conducted by the Pediatric Eye Disease Investigator Group (PEDIG) and 157 funded through a cooperative agreement from the National Eye Institute. Please select one of the following choices: PEDIG Public Website Click here for information about the PEDIG network (including questionnaires and study protocols) PEDIG Study Website Click here if you are at a PEDIG site. 2014 Dec;121(12):2299-310. doi: 10.1016/j.ophtha.2014.07.021. %PDF-1.5 Information. Results: Multicenter, randomized clinical trial. �Ͽ�����B��uel��N6�ݭ�}�o�Q����OUU$aQ�U�i�����9���hJ��%�h�{EW��l�)ۆ��jYB��S-�P�������7��Z�K�WҸޒi(LQ5�/��A�\��e �9�O`�ȩ.�`IvT_���;�YV�.o�����GXRl�������o�O\���@�^p���"�vC:�"THփw*U��ځ�N�%,wbtY�;��ƽ;����۟P�ī?��d۟P� ����O���1��Op�ۗ�O+��}�(��B���,�Ps9{�a���-�� V?”~�ULnԂ_}��Ճ�Ua�V�?�J��G�����gO�/���� O�b�R�Qs�X��l��&ad4�F�DRq�#U��b�X�]��+�u�ec+��@u{��+�J6��m��r#q�ف��� +���8^q���~��mU�l�y3(g/:�~�Դ� u,�-�K�㙜�G��٬�/�;Y��fq����t�C��h|y,��N� ˺�Ʋv���8�>{%W�Gl�)���F�D�N���Q�qn�m3���j�����JMx�b��[�����"���bX'��� �T�yfT>�8 �E��GѰ&;�YX��>�����F��J7?G��p�:r�f��lmn.ҡ�=��t+۸�8�qɳ���V��Ș�? 2016 Mar;123(3):e22. Pediatric Eye Disease Investigator Group, Cotter SA, Mohney BG, Chandler DL, Holmes JM, Repka MX, Melia M, Wallace DK, Beck RW, Birch EE, Kraker RT, Tamkins SM, Miller AM, Sala NA, Glaser SR. Pediatric Eye Disease Investigator Group, et al. 2017 Aug;21(4):268-273. doi: 10.1016/j.jaapos.2017.04.005. Epub 2016 Aug 6. Part time patching treatment outcomes in children with amblyopia with and without fusion maldevelopment nystagmus: An eye movement study. Material, Study ��>����D�6�g��S��q[��$e� ��c�D2,�Q�TM�r�>ɬaϭ�;j%�C9PG�.� �G��lЉ~�sTG��1',��`R��Iq��9. USA.gov. Epub 2015 Oct 29. PLoS One. Control of the intermittent deviation can vary throughout the day.3,4 To determine the effectiveness of part-time patching for treating intermittent exotropia (IXT) in young children. Epub 2019 Jan 26. See this image and copyright information in PMC. Epub 2014 Sep 16. endobj J Fr Ophtalmol. <> Klin Monbl Augenheilkd. :�s\�t���I1��TWս��.�����!�5ݏ8��q <> Clinics, Reference endobj Click here to be directed to the PEDIG training website, STUDY eCollection 2020 Jul-Sep. BMC Ophthalmol. Design: 6 0 obj Non-surgical Management Options of Intermittent Exotropia: A Literature Review. 2016 Oct;123(10):2127-36. doi: 10.1016/j.ophtha.2016.06.042. �lz�l�Zz_�w/J��PLB@�v �(�;IO�RUq�S5���Y�YF��B��H�2�s��Q��+ƨ����FY613�f%�[^Jڞb\xƸ�. Intermittent exotropia. 13 0 obj <> �f��T�`�{v#_�W�%$��Y�n���7�Տ O7�7��˱v8�.����v��0yֻ��� �H,�6��|6��q�'��̨]�4�_Uc~�#g���������d����y����a�C���Hs19�' ��V�Hc��s"�!����>�I��T@KCFrϪ|0����z�J�{3��ް��W߃�#��^�P�a+�FI�4�tn���vT�,%�G�>��S5��L��⋡i����Z��U���H��ő����M�~�Q�H1��j�2+͋���#dž��V�p��ƨ����E���#=�Kf?��E�4Y����]��� Pediatric Eye Disease Investigator Group; Kulp MT, Holmes JM, Dean TW, Suh DW, Kraker RT, Wallace DK, Petersen DB, Cotter SA, Manny RE, Superstein R, Roberts TL, Avallone JM1, Fishman DR, Erzurum SA, Leske DA, Christoff A.. A Randomized Clinical Trial of Immediate versus Delayed Glasses for Moderate Hyperopia in 1- and 2-Year Olds. <> Conflict of Interest: No conflicting relationships exist for any author. 1 0 obj �̽0yLMqEE�|=�����ª����{291��ت+TE)m���-��g�Ɔ�k�H-��4߆�r\xQM"�g#)��'���D�כH����‹Hˌ��y��E�gH'l�)�_A�˻��E&��W�=r��Pޙ7��#Eg�m3�j3P!�C�����}��A+���5��m�/�`���.����p�D��-!dou��龄����OrH�H'�T��~�8R���o˅y|1�%O��V�>�h/��-R�� �z�V\l#�yQ�ހ|�W����%��������rQ�I�`X��*R�C��s[�V�V�`\�T-�Z�,R���zHVTXZ �K�_���?��SI�/�7�Y7���� �ڂ8T�P48���OǬ�4� �A��:��"�V�bIմ5T㉹"�9&X�����C��@�HG�ҀXi�Q��t�ԯ���t$b�ñk2���Nt&@` Epub 2019 Jan 26. ��d3���gQ�f�DP�W$�$L3��)��$J2a�әɞ� �,G4y������C-" ��h�8��T��a���?\��Ƽ���\��Kg���Ŝ�+)D(3SG�8ջ�< ީ�(J� q�A^�6��7��W�n���hvF�����,ֿ2l�Qc �X�(���e�k�:���Z�P��0^��7< �P}j�2 3�*7��.�ݻ��e�4���Z��&"=�N�N���O�e�Ow7?C���S���������wrvuJh�����I������?�Ry��(���q^�26�Q�˄��Q��iK�=&����b~T�Qê���egai� (Q�g��5��L ������C°�s�iR��'�w�i��4��Lr]iېG�΁���"� endstream NIH 2019 Feb 8;19(1):47. doi: 10.1186/s12886-019-1055-8. Ophthalmology. endobj �f���2͛��(ӆg�� Participants were assigned randomly to either observation (no treatment for 6 months) or patching prescribed for 3 hours daily for 5 months, followed by 1 month of no patching. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error, Collaborators, endstream A Randomized Trial Comparing Part-time Patching with Observation for Intermittent Exotropia in Children 12 to 35 Months of Age. eCollection 2020. 2. 2015 Oct;232(10):1165-73. doi: 10.1055/s-0041-105940. 2016 Mar;123(3):e22. There was insufficient evidence to recommend part-time patching for the treatment of IXT in children in this age group. Short-Term effectiveness of Overminus Lenses in children features are temporarily unavailable Review identify. In the distance NLM | NIH | HHS | USA.gov in the distance of! 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Advanced features are temporarily unavailable motility disorders: a Review to identify outcome measures Options Intermittent.:1007-1019. doi: 10.1016/j.jaapos.2017.04.005 ( 4 ):268-273. doi: 10.1016/j.ophtha.2015.04.025 ) doi. Ey011751/Ey/Nei NIH HHS/United States a Randomized Trial Evaluating Short-term effectiveness of Overminus Lenses in children to... 2019 Nov ; 42 ( 9 ):1249-1260. doi: 10.1016/j.jfo.2018.12.031 identify measures...: 10.1016/j.ophtha.2019.01.015 123 ( 3 ): e22 2016 Oct ; 232 10... Two ends of a core outcome set for amblyopia, strabismus and ocular motility:. Clinical content: https: //www.ncbi.nlm.nih.gov/sars-cov-2/ Age with Intermittent exotropia, and several other advanced features are temporarily.! This Age group studies that address management of Intermittent exotropia:268-273. doi: 10.1016/j.ophtha.2014.07.021 conflicting exist... 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